Animal House Facility

The Animal House facility, established in the year 2023, is located at the Department of Biotechnology and Bioinformatics in the Sambalpur University campus away from the crowded environment which provides a healthy environment for animal management. It is the backbone of research activities for Drug Discovery and drug development. The Animal House facility has its own institutional Animal Ethics Committee constituted specifically to address scientific and ethical considerations of animal use for research. The Animal House facility is registered and approved by the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA), Ministry of Environment and Forests, Government of India, for conducting experiments on small animals. It has Instrumentation room, well equipped with modern digital equipment’s like Analgesia meter-hot and cold plate, Plethysmometer, Infrared Actimeter System, Rotarod Apparatus, Electroconvulsiometer, Cook’s Pool Climbing Apparatus, Auto Hematology Analyzer, Dissection Table, Anaesthesia System, Water maze, Y maze, Elevated Plus maze. It has also quarantine, Individual animal rooms for small Rodents and Rabbit, experimental room, Dissection room, Animal Behaviour study room for animal experiments.
INSTRUMENT DETAILS
1. ANALGESIA METER-HOT AND COLD PLATE
Model:HC-01
Make:ORCHID SCIENTIFIC
Uses:
The Hot/Cold Plate Analgesia Meter is an innovative instrument opening new investigation fields for our analgesia research by allowing us to test animal's sensitivity to pain resulting from exposure to heat or cold.It is developed to perform rapid & precise screening of analgesic drug properties on mice & rat.

ANALGESIA METER-HOT AND COLD PLATE
2. DIGITAL PLETHYSMOMETER
Model:PLM 01 PLUS
Make:ORCHID SCIENTIFIC
Uses:
The Digital Plethysmometer is useful Apparatus to measure the changes in small paw volume indicating inflammation. This Apparatus measures micro volume changes due to displacement of water with the insertion of Rat or Mouse paw.

DIGITAL PLETHYSMOMETER
3. INFRARED ACTIMETER SYSTEM
Model:ACT-01
Make:ORCHID SCIENTIFIC
Uses:
The Infrared (IR) Actimeter allows the study of spontaneous locomotor activity, rearings and optionally hole-board test parameters for exploration in rodents. A reliable system for easy and rapid drug screening and phenotype characterisation in both day and night conditions.

INFRARED ACTIMETER SYSTEM
4. ROTAROD APPARATUS
Model:RR 01
Make:ORCHID SCIENTIFIC
Uses:
The RotaRod Apparatus is used for assessing motor coordination and balance in rodents. It provides a quick and simple estimation of neuromuscular coordination.

ROTAROD APPARATUS
5. DIGITAL ELECTROCONVULSIOMETER
Model:EC-02
Make:ORCHID SCIENTIFIC
Uses:
Electroconvulsiometer is used for applying maximal electro-shock through corneal electrodes provided.This Instrument is used to study the anti-convulsant activity of phenytoin against maximal electro-shock induced convulsions in rat or mice.

DIGITAL ELECTROCONVULSIOMETER
6. DIGITAL COOK’S POOL CLIMBING APPARATUS
Model:CP-01
Make:ORCHID SCIENTIFIC
Uses:
Digital Cook's pole climbing apparatus is used to determine the antipsychotic activity and is based on principle of ability of psychotropic drugs to avoid conditioned response. This apparatus is used for inducing stable baseline behavior.

DIGITAL COOK’S POOL CLIMBING APPARATUS
7. AUTO HEMATOLOGY ANALYSER
Model:SMART-5DX
Make:Byovet
Uses:
Automated hematology analyzer can rapidly analyze whole blood specimens for the complete blood count (CBC). Results include red blood cell (RBC) count, white blood cell (WBC) count, platelet count, hemoglobin concentration, hematocrit, RBC indices, and a leukocyte differential.

AUTO HEMATOLOGY ANALYSER
8. Dissection Table
Model:PSW-01
Make:ORCHID SCIENTIFIC
Uses:
Dissecting tools will be used to open the body cavity of the rat and observe the structures.

Dissection Table
9. Anesthesia system
Model:PSW-01
Make:SENATEPRO
Uses:
The Anaesthesia System is to prepare a gas mixture of precisely known, but variable composition. The gas mixture can then be delivered to a breathing system. The anesthesia gas machine is also called the anesthesia workstation, or anesthesia delivery system.

Anesthesia system
10. Water maze
Model:NA
Make:ORCHID SCIENTIFIC
Uses:
Animal Behavioural studies

Water maze
11. Y maze
Model:NA
Make:ORCHID SCIENTIFIC
Uses:
Animal Behavioural studies

Y maze
12. Elevated Plus maze
Model:NA
Make:ORCHID SCIENTIFIC
Uses:
Animal Behavioural studies

Elevated Plus maze
13. Semi-Automatic Cryostat Microtome
Model:MCM-ST
Make:Leica
Uses:
It is used to preserves the frozen tissue samples, slice tissue sections thin enough for microscopic examination, and provide a quick diagnosis for a variety of diseases and medical conditions, including neuromuscular diseases. It can also be used to examine enzyme histochemistry.

Semi-Automatic Cryostat Microtome